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. 2021 Jan 28;31(7):773–790. doi: 10.1038/s41422-020-00464-8

Fig. 1. COMP is downregulated in both AAA patients and mice.

Fig. 1

a Plasma COMP levels measured by an ELISA in patients with AAA (Case, n = 88), patients with arteriosclerosis obliterans of the lower limbs without AAA (Control, n = 88) and healthy volunteers (n = 51). Data are presented as boxes (median with 1st quartile and 3rd quartile) and whiskers (minimum to maximum). *P < 0.05 by Wilcoxon signed-rank test; NS, no significance by Mann-Whitney test. b Representative western blot and quantitative analysis of the COMP protein level in the suprarenal aortas of ApoE–/– mice infused with 1000 ng/kg/min AngII or saline for 7 days. n = 6 mice per group; *P < 0.05 by Mann-Whitney test.