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. 2021 Jul 1;7:14. doi: 10.1038/s41514-021-00067-6

Fig. 1. MindCrowd: age, paired-associate learning (PAL), and biological sex.

Fig. 1

MindCrowd analysis (ages 18–85) of simple visual reaction time (svRT). a Linear model fits (line fill ±95% CI, error bars ± SEM) of the median svRT by Age3 (curvilinear model). There was a curvilinear relationship between svRT and Age1 (βAge1 = 7.07, pAge1 = 3.06E − 18), Age2 (βAge2 = −0.15, pAge2 = 3.23E − 17), and Age3 (βAge3 = 1.47E − 03, pAge3 < 1.46E − 34, n = 75,666). b Linear model fits (line fill ±95% CI, error bars ± SEM) of the median svRT by Age3 (curvilinear model). There was a curvilinear relationship between svRT and paired-associate learning (PAL) performance PAL Performance1 (βPAL1 = −8.89, pPAL1 = 3.77E − 34), PAL Performance2 (βPAL2 = 0.32, pPALl2 = 2.35E − 14), and PAL Performance3 (βPAL3 = −4.13E − 03, pPAL3 = 7.28E − 09, n = 75,666). c Simple slope analysis of the linear model fit (line fill ±95% CI, error bars ± SEM) for the Median svRT × PAL Performance interaction (βAge*PAL = −0.07, pAge*PAL = 1.26E − 59). At 20 (βAge20*PAL = −5.48, pAge20*PAL < 0.00, n = 1985), 40 (βAge40*PAL = −6.41, pAge40*PAL < 0.00, n = 739), 60 (βAge60*PAL = −7.75, pAge60*PAL < 0.00, n = 1789), and 80 (βAge80*PAL = −9.08, pAge80*PAL < 0.00, n = 344) years of age. d Linear model fits (line fill ±95% CI, error bars ± SEM) of the median svRT by Age3 (curvilinear model) with lines split by Biological Sex. Being a woman was associated with longer svRT compared to being a man from younger to older ages (βSex = −34.26, pSex = 1.26E − 163, nWomen = 47,700, nMen = 27,966).