Table 5.
Summary of the key results from UKBb MindCrowd and the UK Biobank.
| UKBb MindCrowd | The UK Biobank | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variable | Value | β | SE | t | p | β | SE | t | p | |
| Intercept | 189.77 | 10.65 | 18.35 | 6.46E − 75 | 335.93 | 1.69 | 209.93 | 2.00E − 16 | Agree | |
| Age | Per year | 5.75 | 0.12 | 46.57 | 2.00E − 16 | 3.40 | 0.03 | 132.87 | 2.00E − 16 | Agree |
| Biological sex | Men | −40.00 | 2.24 | −17.83 | 8.03E − 71 | −18.28 | 0.38 | −47.70 | 2.00E − 16 | Agree |
| Diabetes mellitus | True | 11.48 | 3.91 | 2.94 | 3.31E − 03 | 5.48 | 1.09 | 5.03 | 4.80E − 07 | Agree |
| Handedness | Left | −2.58 | 3.05 | −0.85 | 4.00E − 01 | 0.58 | 0.63 | 0.92 | 0.36 | N.S. in both-but MindCrowd subtle effect |
| Reported stroke | True | 18.47 | 9.02 | 2.05 | 4.00E − 02 | 10.61 | 2.13 | 4.99 | 6.15E − 07 | Agree |
| Reported hypertension | True | 6.99 | 2.37 | 2.95 | 3.16E − 03 | 1.09 | 0.48 | 2.27 | 2.00E − 02 | Agree |
| Smoking status | True | 10.18 | 3.87 | 2.63 | 0.01 | 0.40 | 0.38 | 1.05 | 0.29 | MindCrowd Finding: Both Primary and UKBb |
| Reported dizziness | True | 12.10 | 4.00 | 3.02 | 2.52E − 03 | 3.21 | 0.42 | 7.57 | 3.71E − 14 | Agree |
| Educational attainment | High school diploma | −9.68 | 8.77 | −1.10 | 2.70E − 01 | −9.68 | 0.80 | −12.09 | 1.23E − 33 | Agree |
| Educational attainment | Some college | −26.08 | 8.27 | −3.15 | 1.61E − 03 | −10.26 | 0.77 | −13.35 | 1.30E − 40 | Agree |
| Educational attainment | College degree | −49.07 | 8.17 | −6.01 | 1.91E − 09 | −11.71 | 0.87 | −13.51 | 1.46E − 41 | Agree |
| First-degree family history of Alzheimer’s disease | True | −0.07 | 2.06 | −0.04 | 0.97 | 2.43 | 0.57 | 4.26 | 2.04E − 05 | UK Biobank Finding |
| Age × biological sex | Men’s vs. women’s per year change in Age slope | −0.62 | 0.26 | −2.38 | 2.00E − 02 | −0.55 | 0.05 | −10.99 | 4.18E − 28 | Agree |
| Biological sex by educational attainment | Men with high school diploma vs. women with no high school diploma | 21.63 | 19.62 | 1.10 | 0.27 | −11.24 | 1.61 | −6.96 | 3.30E − 12 | UK Biobank Finding |
| Biological sex by educational attainment | Men with some college vs. women with no high school diploma | 16.25 | 18.28 | 0.89 | 0.37 | −10.54 | 1.54 | −6.83 | 8.71E − 12 | UK Biobank Finding |
| Biological sex by educational attainment | Men with a college degree vs. women with no high school diploma | 14.79 | 17.94 | 0.82 | 0.41 | −12.8 | 1.74 | −7.37 | 1.68E − 13 | UK Biobank Finding |
Displayed are factor names, factor definitions, β = unstandardized regression coefficients, as well as estimate SE = standard error, t = value of t-statistic, and p = p-value across both cohorts. The last column displays model outcomes in terms of the agreement between UKBb MindCrowd and the UK Biobank.