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. 2021 Jul 2;54(8):1841–1852.e4. doi: 10.1016/j.immuni.2021.06.015

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© 2021 The Author(s)

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Potently neutralizing monoclonal antibodies fail to neutralize VOCs 501Y.V2 and 501Y.V3

(A–L) Levels of neutralization by serially diluted neutralizing monoclonal antibodies were quantitated on the basis of the prevention of cytopathic effects. Resistance of 501Y.V1 (QHN002) (A–D), 501Y.V3 (TY7-503) (E–H), and 501Y.V2 (TY8-612) (I–L) was compared with that of the Wuhan strain. Data are plotted as mean ± SD with sigmoidal curves. Representative data from three independent experiments are shown.