Table 1.
Patient's characteristics
| Parameter | Total Participants (n = 25) | Low muscularity*(n = 12) | High muscularity*(n = 12) | §p-value | Survivors (n = 18) | Non-Survivors (n = 7) | #p-value |
|---|---|---|---|---|---|---|---|
| Age, y | 67 (60; 78) | 67 (58; 71) | 67 (62; 78) | 0.422 | 64 (59; 68) | 78 (70; 79.5) | 0.034 |
| Male, (%) | 14 (56) | 7 (58) | 7 (58) | >0.99 | 9 (50) | 5 (71) | 0.332 |
| Hemoglobin, g/dL | 12.9 ± 2.0 | 12.3 ± 2.2 | 13.5 ± 1.7 | 0.138 | 12.5 ± 2.2 | 14.0 ± 0.7 | 0.081 |
| White blood cell count, /μL | 9590 ± 4854 | 9955 ± 4269 | 8625 ± 5224 | 0.502 | 8462 ± 4164 | 12492 ± 5609 | 0.061 |
| Lymphocyte count, /μL | 720 (550; 1130) | 740 (430; 1200) | 710 (595; 1110) | 0.760 | 695 (467.5; 890) | 1200 (720; 1410) | 0.174 |
| Neutrophil count, /μL | 8066 ± 4670 | 8980 (6725; 10600) | 5890 (4870; 7538) | 0.215 | 7063 ± 3563 | 10643 ± 6364 | 0.085 |
| Neutrophil-Lymphocyte Ratio | 8.52 (5.25; 16.02) | 11.65 (5.45; 17.34) | 6.22 (5.06; 11.18) | 0.401 | 9.34 (5.55; 14.33) | 5.79 (4.86; 19.19) | 0.976 |
| Albumin, g/dL | 3.2 ± 0.5 | 3.2 ± 0.4 | 3.3 ± 0.6 | 0.479 | 3.2 ± 0.5 | 3.3 ± 0.6 | 0.667 |
| CRP, mg/dl | 15.6 (9.4; 19.2) | 15.3 (12.4; 19.3) | 14.8 (8.9; 19.8) | 0.841 | 18.1 (11.6; 19.5) | 12.3 (7.4; 16.8) | 0.263 |
| Orotracheal Intubation, (%) | 15 (60) | 7 (58) | 7 (58) | >0.99 | 8 (44) | 7 (100) | 0.020 |
| Anthropometric and body composition indices | |||||||
| BMI, kg/m2 | 28.8 ± 4.8 | 29.4 ± 5.7 | 28.3 ± 4.0 | 0.589 | 28.98 ± 5.47 | 28.20 ± 2.75 | 0.724 |
| BMI 25, (%) | 19 (76) | 8 (67) | 10 (83) | 0.346 | 12 (67) | 7 (100) | 0.137 |
| BMI 18.5–24.9, (%) | 6 (24) | 4 (33) | 2 (17) | 0.346 | 6 (33) | 0 (0) | 0.137 |
| Waist circumference, cm | 113 ± 23 | 117 ± 26 | 112 ± 21 | 0.603 | 117 ± 25 | 103 ± 13 | 0.191 |
| Arm circumference, cm | 31 ± 4 | 31 ± 3 | 31 ± 4 | 0.913 | 31 ± 4 | 31 ± 3 | 0.808 |
| SMA, cm2 | 71 (61.75; 77.25) | 62 (54; 71) | 78 (71; 98) | 0.001 | 71 (62.5; 76.25) | 72.5 (64.25; 77) | 0.741 |
| SMI, cm2/m2 | 24.86 (23.36; 25.69) | 22.99 (20.44; 24.12) | 25.78 (25.35; 33.81) | <0.0001 | 25 (22.63; 25.4) | 25 (24.08; 25.86) | 0.667 |
| Comorbidities | |||||||
| Hypertension, (%) | 13 (52) | 7 (58) | 5 (42) | 0.414 | 8 (44) | 5 (71) | 0.225 |
| Diabetes, (%) | 4 (16) | 2 (17) | 2 (17) | >0.99 | 3 (17) | 1 (14) | 0.884 |
| Chronic kidney disease, (%) | 2 (8) | 1 (8) | 1 (8) | >0.99 | 1 (6) | 1 (14) | 0.470 |
| Complications | |||||||
| Acute kidney injury, % | 5 (20) | 2 (17) | 2 (17) | >0.99 | 0 (0) | 5 (71) | 0.0004 |
| Embolic events, % | 6 (24) | 5 (71) | 1 (8) | 0.059 | 3 (17) | 3 (43) | 0.169 |
| Bleedings, % | 4 (16) | 4 (33) | 0 (0) | 0.271 | 3 (17) | 1 (14) | 0.884 |
Abbreviations. CRP, C-reactive protein; BMI, body mass index; SMA, skeletal muscle area, SMI, skeletal muscle index
Data are shown as mean ± standard deviation and median (interquartile range) for nonnormally distributed variables.
⁎
Muscularity (SMI) available in 24 out of 25 patients
§
patients with low muscularity (below the sex-specific median value of SMI) vs patients with high muscularity (over the sex-specific median value of SMI)
#
survivors vs non-survivors.