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In vitro profile of YTH‐60 against a panel of 11 kinases
| Kinase | IC50 a (nmol·L−1) |
|---|---|
| Abl (h) | 27 |
| FGFR1 (h) | 4 |
| FGFR2 (h) | 7 |
| FGFR3 (h) | 9 |
| FGFR4 (h) | 424 |
| Flt1 (h)/VEGFR1 | 123 |
| Flt3 (h) | 297 |
| Flt4 (h)/VEGFR3 | 64 |
| KDR (h)/VEGFR2 | 61 |
| PDGFRα (h) | 921 |
| PDGFRβ (h) | >3000 |
| Src (1‐530) (h) | 633 |
The biochemical tests were provided by Eurofins Discovery. All data were obtained by double testing.
