FIGURE 6.

Probiotics ameliorate periapical bone loss in OVX rats. A, H&E staining indicating periapical bone loss of mesial root of mandibular first molar (area within the red line). Scale bar = 100 μm. (B,C) Representative micro‐CT images of periapical lesion of mesial root of mandibular first molar (white arrow) and quantitative analysis of resorption volume in periapical regions. Data are presented as the mean ± SD, n = 5‐8 rats per group. The p values are indicated above the horizontal bars. lsPro, life space probiotics; Veh, Vehicle