Fig. 3.

Showing the relationship between excito-toxicity and the beneficial effect of magnesium in it. Excess of calcium influx in brain may cause causes various complication in brain such as excitotoxicity, BBB disruption, inflammation and oxidative stress. Magnesium is found to be beneficial in neurological diseases via correcting the above mentioned complications. i.e., inhibiting calcium influx, substance P production, inflammation and oxidative stress. ROS reactive oxygen species, NMDA receptor N methyl D aspartate receptor, BBB blood brain barrier