Histopathology of the 3 cases. A, Case 1 had marked dyskeratosis and epidermal dysmaturation with a sparse superficial perivascular infiltrate of lymphocytes and eosinophils and a subtle vacuolar interface. Biopsy location: left upper portion of the arm. B, Case 2 had spongiosis with epidermal necrosis and infiltrate with eosinophils. Biopsy location: right upper portion of the arm. C, Case 3 had epidermal atypia, apoptosis, and superficial perivascular dermatitis with eosinophils and focal interface change. Biopsy location: abdomen. (A, B, and C, Hematoxylin-eosin stain; original magnification: ′20.)