Table 3.
Multivariable Cox proportional of OS and DFS.
| Variables | OS (Before matching) | OS (After matching) | DFS (Before matching) | DFS (After matching) | ||||
|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Tumour differentiation (Poor) | 1.95 (1.10,2.40) | 0.034 | 1.85 (1.06,2.32) | 0.019 | 2.45 (1.02,2.60) | 0.034 | 2.02 (1.02,2.42) | 0.027 |
| Nerve invasion (Yes) | 1.64 (1.13,1.76) | 0.012 | 1.58 (1.13,1.61) | 0.042 | 1.89 (1.06,1.96) | 0.019 | 1.75 (1.10,1.86) | 0.032 |
| Postoperative Chemotherapy (No) | 1.54 (1.01,1.98) | <0.001 | 1.64 (1.02,1.78) | <0.001 | 1.63 (1.22,1.79) | <0.001 | 1.54 (1.32,1.70) | <0.001 |
| MOR expression (high) | 1.25 (0.93,1.70) | 0.264 | 1.08 (0.96,1.38) | 0.125 | 1.23 (0.90,1.72) | 0.326 | 1.19 (0.94,1.43) | 0.167 |
OS, Overall Survival; DFS, Disease free Survival; MOR, Mu-Opioids Receptor.