Table 2.
Echocardiographic characteristics of all patients.
| All patients (n = 105) | Patients who met the endpoint (n = 31) | Patients who did not meet the endpoint (n = 74) | p-value | |
|---|---|---|---|---|
| LVEDD (mm) | 63.8 ± 9.4 | 68.5 ± 7.8 | 61.9 ± 9.4 | 0.001 |
| LVEDDI (mm/m2) | 31.1 ± 5.1 | 33.2 ± 5 | 30.3 ± 5 | 0.006 |
| FS (%) | 12.8 ± 8 | 10.3 ± 9.1 | 13.3 ± 7.4 | 0.076 |
| LVEDV—Simpson (ml) | 227 ± 88 | 246 ± 64 | 218 ± 95 | 0.14 |
| LVEDVI—Simpson (ml/m2) | 109 ± 39 | 119 ± 32 | 105 ± 41 | 0.09 |
| LVEF—Simpson (%) | 27.8 ± 8.2 | 22.2 ± 5.8 | 30.1 ± 8 | <0.0001 |
| LVOT VTI (cm) | 14.8 ± 4.1 | 11.8 ± 2.5 | 16 ± 3.9 | <0.0001 |
| SV—LVOT (ml) | 53.1 ± 14.8 | 42.5 ± 11.6 | 57.5 ± 13.7 | <0.0001 |
| Mitral regurgitation | 0.001 | |||
| None | 25 (23.8) | 2 (6.5) | 23 (31.1) | |
| Mild | 45 (42.9) | 11 (35.5) | 34 (45.9) | |
| Moderate | 21 (20) | 9 (29) | 12 (16.2) | |
| Severe | 14 (13.3) | 9 (29) | 5 (6.8) | |
| Tricuspid regurgitation | 0.14 | |||
| None | 49 (46.7) | 11 (35.5) | 38 (51.4) | |
| Mild | 39 (37.1) | 12 (38.7) | 27 (36.5) | |
| Moderate | 11 (10.5) | 4 (12.9) | 7 (9.5) | |
| Severe | 6 (6) | 4 (12.9) | 2 (2.7) | |
| PA pressure (mmHg) | 30.4 ± 11.8 | 34 ± 11.5 | 28.5 ± 11.6 | 0.1 |
| TAPSE (mm) | 19.9 ± 4.5 | 18 ± 3.5 | 20.7 ± 4.6 | 0.005 |
| E-velocity (m/s) | 0.83 ± 0.3 | 0.97 ± 0.3 | 0.77 ± 0.3 | 0.002 |
| E/e' average | 17.5 ± 8.8 | 21.6 ± 9 | 15.7 ± 8.1 | 0.002 |
| Deceleration time (ms) | 159 ± 64 | 142 ± 66 | 167 ± 62 | 0.081 |
| Global longitudinal strain (%) | −7.1 ± 3.2 | −4.9 ± 2.1 | −7.97 ± 3.2 | <0.0001 |
| GWE (mmHg%) | 76.2 ± 10.3 | 72.2 ± 8.3 | 77.9 ± 10.6 | 0.009 |
| GWI (mmHg%) | 603 ± 329 | 378 ± 173 | 697 ± 334 | <0.0001 |
| GCW (mmHg%) | 742 ± 363 | 497 ± 210 | 845 ± 366 | <0.0001 |
| GWW (mmHg%) | 164 ± 92 | 143 ± 69 | 173 ± 99 | 0.13 |
| GPW (mmHg%) | 755 ± 357 | 508 ± 210 | 858 ± 355 | <0.0001 |
| GSCW (mmHg%) | 695 ± 339 | 467 ± 198 | 791 ± 341 | <0.0001 |
Values are given as a number (percent) or mean ± standard deviation except where otherwise indicated.
LVEDD, left ventricular end-diastolic diameter; LVEDDI, left ventricular end-diastolic diameter index; LVEDV, left ventricular end-diastolic volume; LVEDVI, left ventricular end-diastolic volume index; LVEF, left ventricular ejection fraction; LVOT VTI, left ventricular outflow tract velocity time integral; SV—LVOT, stroke volume calculated by continuity equation; PA, pulmonary artery calculated from peak tricuspid regurgitation velocity; TAPSE, tricuspid annular plane systolic excursion; GWE, global work efficiency; GWI, global work index; GCW, global constructive work; GWW, global wasted work; GPW, global positive work; GSCW, global systolic constructive work.