Table 4. Comparison results with state-of-the-art methods (%).
| Methods | MCI vs. NC | AD vs. NC | AD vs. MCI | AD vs. MCI vs. NC | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACC | SPE | SEN | PRE | F1 | AUC | ACC | SPE | SEN | PRE | F1 | AUC | ACC | SPE | SEN | PRE | F1 | AUC | ACC | SPE | SEN | PRE | F1 | AUC | ||||
| ROI | 77.1 | 79.7 | 74.5 | 76.3 | 76.0 | 81.4 | 83.1 | 85.6 | 80.1 | 81.4 | 80.7 | 87.4 | 70.0 | 73.0 | 66.5 | 67.0 | 66.8 | 73.0 | 58.0 | 78.9 | 58.4 | 57.7 | 58.0 | 63.1 | |||
| Patch | 73.5 | 68.6 | 78.4 | 70.6 | 74.3 | 79.7 | 82.9 | 88.6 | 75.1 | 84.6 | 79.4 | 90.7 | 69.1 | 70.3 | 67.4 | 65.4 | 66.1 | 76.8 | 60.5 | 80.2 | 60.5 | 60.0 | 60.2 | 63.8 | |||
| WI | 77.7 | 79.5 | 75.9 | 77.5 | 76.6 | 86.3 | 88.1 | 90.2 | 85.2 | 87.6 | 86.4 | 94.3 | 72.4 | 71.4 | 73.5 | 68.1 | 70.6 | 78.6 | 60.9 | 80.2 | 63.6 | 59.8 | 61.6 | 63.9 | |||
| Att | 76.0 | 77.7 | 74.2 | 76.3 | 75.1 | 82.9 | 86.1 | 89.6 | 82.6 | 86.3 | 83.9 | 93.5 | 75.5 | 77.3 | 72.6 | 73.9 | 72.8 | 81.5 | 59.8 | 79.7 | 60.9 | 60.1 | 60.5 | 64.1 | |||
| Our | 80.1 | 80.3 | 78.2 | 79.2 | 78.6 | 85.0 | 92.0 | 93.1 | 90.3 | 91.6 | 90.9 | 96.2 | 80.7 | 81.0 | 79.9 | 77.6 | 78.7 | 86.2 | 62.9 | 81.8 | 64.5 | 61.6 | 62.9 | 64.9 | |||
MCI, mild cognitive impairment; NC, normal control; AD, Alzheimer’s disease; ROI, region of interest; WI, the whole image-based method; Att, the attention-based method; ACC, accuracy; SPE, specificity; SEN, sensitivity; PRE, precision; F1, F1-score; AUC, area under the curve.