Table 5. Selection of the hyper-parameter K (%).
| Number of patches | MCI vs. NC | AD vs. NC | AD vs. MCI | AD vs. MCI vs. NC | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACC | SPE | SEN | PRE | F1 | AUC | ACC | SPE | SEN | PRE | F1 | AUC | ACC | SPE | SEN | PRE | F1 | AUC | ACC | SPE | SEN | PRE | F1 | AUC | ||||
| 3 | 77.0 | 74.7 | 81.2 | 75.6 | 78.3 | 82.5 | 90.8 | 91.8 | 89.6 | 89.5 | 89.5 | 95.5 | 75.3 | 78.6 | 71.8 | 73.9 | 72.3 | 82.1 | 60.8 | 80.3 | 61.4 | 60.1 | 60.8 | 64.6 | |||
| 4 | 77.6 | 76.8 | 78.6 | 76.7 | 77.6 | 84.7 | 92.0 | 93.1 | 90.3 | 91.6 | 90.9 | 96.2 | 76.5 | 76.2 | 76.4 | 72.8 | 74.5 | 81.4 | 61.0 | 80.6 | 60.6 | 60.6 | 60.6 | 64.8 | |||
| 5 | 79.4 | 79.0 | 79.6 | 78.6 | 79.0 | 86.0 | 91.5 | 88.1 | 90.7 | 90.1 | 90.5 | 96.5 | 78.0 | 82.0 | 73.1 | 77.0 | 74.9 | 83.0 | 62.8 | 81.3 | 62.8 | 62.4 | 62.6 | 65.1 | |||
| 6 | 81.0 | 80.0 | 80.2 | 79.3 | 79.8 | 86.1 | 90.2 | 92.5 | 87.5 | 90.4 | 88.8 | 95.6 | 80.7 | 81.0 | 79.9 | 77.6 | 78.7 | 86.2 | 62.9 | 81.8 | 64.5 | 61.6 | 62.9 | 64.9 | |||
| 7 | 79.2 | 77.6 | 80.8 | 77.82 | 79.3 | 86.7 | 89.1 | 90.4 | 87.7 | 88.1 | 87.8 | 94.8 | 79.3 | 78.2 | 77.0 | 75.3 | 77.7 | 86.1 | 62.3 | 81.1 | 62.1 | 61.7 | 61.9 | 62.9 | |||
| 8 | 78.4 | 78.8 | 77.8 | 77.7 | 77.8 | 85.6 | 90.8 | 91.5 | 87.2 | 89.8 | 88.3 | 95.3 | 80.6 | 81.9 | 79.2 | 78.1 | 78.6 | 86.4 | 61.7 | 80.8 | 62.5 | 61.0 | 61.8 | 63.5 | |||
| 9 | 77.6 | 79.3 | 75.7 | 78.2 | 76.8 | 84.1 | 89.4 | 90.8 | 87.5 | 88.3 | 87.9 | 94.9 | 76.2 | 77.9 | 74.2 | 73.4 | 73.7 | 82.2 | 61.5 | 80.8 | 61.3 | 61.2 | 61.3 | 63.9 | |||
| 10 | 77.5 | 77.4 | 75.6 | 76.6 | 76.0 | 83.7 | 88.4 | 90.4 | 85.7 | 87.6 | 86.3 | 94.0 | 74.8 | 75.2 | 73.0 | 71.0 | 72.0 | 79.3 | 60.2 | 80.1 | 60.2 | 59.7 | 59.9 | 64.4 | |||
| 20 | 77.5 | 75.2 | 81.3 | 75.7 | 77.6 | 83.5 | 88.7 | 90.6 | 86.6 | 88.0 | 87.2 | 95.3 | 74.0 | 70.4 | 78.0 | 68.6 | 73.0 | 79.0 | 57.9 | 78.9 | 58.3 | 56.9 | 57.6 | 61.4 | |||
| 30 | 75.8 | 78.0 | 73.7 | 76.3 | 74.9 | 82.3 | 84.3 | 88.7 | 79.1 | 84.6 | 81.6 | 91.1 | 74.0 | 80.9 | 65.3 | 73.8 | 69.3 | 77.2 | 57.5 | 78.9 | 57.3 | 56.8 | 57.1 | 62.4 | |||
MCI, mild cognitive impairment; NC, normal control; AD, Alzheimer’s disease; ACC, accuracy; SPE, specificity; SEN, sensitivity; PRE, precision; F1, F1-score; AUC, area under the curve.