Table 6. Ablation study of the visual and semantic attention modules in HAS (%).
| Visual attention | Semantic attention | MCI vs. NC | AD vs. NC | AD vs. MCI | AD vs. MCI vs. NC | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACC | SPE | SEN | PRE | F1 | AUC | ACC | SPE | SEN | PRE | F1 | AUC | ACC | SPE | SEN | PRE | F1 | AUC | ACC | SPE | SEN | PRE | F1 | AUC | |||||
| × | × | 78.0 | 80.2 | 75.4 | 76.7 | 76.1 | 84.3 | 90.5 | 90.9 | 89.9 | 88.7 | 89.3 | 95.8 | 78.6 | 80.4 | 76.3 | 76.2 | 76.2 | 85.1 | 58.5 | 79.6 | 59.6 | 58.4 | 58.5 | 64.0 | |||
| √ | × | 78.4 | 77.6 | 79.4 | 76.6 | 77.9 | 85.0 | 90.6 | 92.3 | 88.5 | 90.1 | 89.2 | 96.5 | 79.1 | 80.6 | 77.3 | 76.6 | 76.8 | 85.2 | 59.8 | 79.9 | 60.1 | 59.4 | 59.8 | 64.6 | |||
| × | √ | 78.7 | 78.4 | 78.9 | 77.2 | 78.0 | 84.4 | 90.6 | 92.1 | 88.5 | 90.4 | 89.4 | 95.9 | 78.9 | 81.0 | 76.0 | 76.7 | 76.4 | 84.7 | 59.9 | 80.1 | 59.4 | 59.4 | 59.4 | 63.3 | |||
| √ | √ | 80.1 | 80.3 | 78.2 | 79.2 | 78.6 | 85.0 | 92.0 | 93.1 | 90.3 | 91.6 | 90.9 | 96.2 | 80.7 | 81.0 | 79.9 | 77.6 | 78.7 | 86.2 | 62.9 | 81.8 | 64.5 | 61.6 | 62.9 | 64.9 | |||
HAS, hierarchical attention sub-network; MCI, mild cognitive impairment; NC, normal control; AD, Alzheimer’s disease; ACC, accuracy; SPE, specificity; SEN, sensitivity; PRE, precision; F1, F1-score; AUC, area under the curve.