Table 1. Baseline characteristics of the patients.
Characteristic | Total (n=65) | Responders (n=28) | Non–responders (n=37) | P value |
---|---|---|---|---|
Age, years | 64 [59–70] | 65 [60–70] | 64 [59–70] | 0.968 |
Male, n (%) | 55 (85%) | 25 (89%) | 30 (81%) | 0.495 |
BMI, kg/m2 | 25±3 | 25±3 | 24±3 | 0.203 |
DM, n (%) | 15 (23%) | 10 (36%) | 5 (14%) | 0.043 |
HTN, n (%) | 39 (60%) | 16 (57%) | 23 (62%) | 0.799 |
CKD, n (%) | 2 (3%) | 2 (7%) | 0 (0) | 0.182 |
LVEF, % | 60±8 | 60±8 | 60±8 | 0.914 |
RVFAC, % | 45±6 | 46±5 | 45±5 | 0.637 |
NT-proBNP, pg/mL | 183 [77–480] | 181 [69–480] | 201 [77–621] | 0.517 |
Lactate, mmol/L | 0.7±0.3 | 0.8±0.2 | 0.7±0.3 | 0.748 |
Tidal volume, mL/kg | 8.1±0.6 | 8.1±0.3 | 8.2±0.8 | 0.445 |
PEEP, cm H2O | 5±0 | 5±0 | 5±0 | 1.000 |
Pplat, cm H2O | 11±2 | 12±2 | 11±2 | 0.269 |
PaO2/FiO2, mmHg | 472±98 | 481±104 | 466±95 | 0.548 |
PaCO2, mmHg | 40±4 | 40±4 | 40±4 | 0.702 |
Patients receiving norepinephrine, n (%) | 42 (65%) | 19 (68%) | 23 (62%) | 0.561 |
Patients receiving dobutamine, n (%) | 10 (15%) | 4 (14%) | 6 (16%) | 0.532 |
Dose of norepinephrine (ìg·kg−1·min−1) | 0.1 [0.2–0.4] | 0.1 [0.2–0.3] | 0.1 [0.3–0.5] | 0.422 |
Dose of dobutamine (ìg·kg−1·min−1) | 0.4 [0.3–0.8] | 0.3 [0.3–0.9] | 0.5 [0.2–0.7] | 0.981 |
Preoperative β-blockers administration, n (%) | 55 (85%) | 23 (82%) | 32 (86%) | 0.734 |
EURO score | 5 [0–9] | 5 [1–8] | 5 [0–9] | 0.408 |
Values are expressed as the mean ± standard deviation, median [25th–75th percentile] or number (percentage). BMI, body mass index; DM, diabetes mellitus; HTN, hypertension; CKD, chronic kidney disease; LVEF, left ventricular ejection fraction; RVFAC, right ventricular fractional area change; NT-proBNP, N-terminal pro-brain natriuretic peptide; PEEP, positive end-expiratory pressure; Pplat, airway pressure platform; PaO2, arterial partial pressure of oxygen; FiO2, inspiratory fraction of oxygen; PaCO2, arterial partial pressure of carbon dioxide; EURO score, European system for cardiac operative risk evaluation.