Table 2. Descriptions of statistically different brain regions between groups in normalized CBF.

Brain regions (AAL)	Peak MNI coordinates (mm)			Peak F value	Cluster size (mm3)
	X	Y	Z
aMCI > HC
Left postcentral gyrus/putamen	−30	−10	0	5.67	3,335
Right putamen	34	−2	−4	5.28	505
Right anterior cingulate gyrus	14	36	12	4.37	320
Right supplementary sports area	14	4	46	5.00	620
Left middle cingulate gyrus	−14	−4	58	4.49	255
aMCI < HC
Right middle frontal gyrus	32	34	46	−5.87	1,963
Left superior frontal gyrus	−24	64	4	−5.74	237
Left medial frontal gyrus	−2	36	40	−4.53	357
Right angular gyrus	52	-58	44	−4.37	534
PD-MCI > HC
Left postcentral gyrus/putamen	-28	-24	10	6.82	2,105
Right putamen	34	-2	8	5.36	291
Right anterior cingulate gyrus	12	30	8	7.11	533
PD-MCI < HC
Right superior frontal gyrus	30	58	0	−5.02	134
Left medial frontal gyrus	−2	54	12	−4.73	605
Right angular gyrus	38	-68	42	−4.97	357
Right middle frontal gyrus	30	32	46	−6.63	1,017
PD-MCI < aMCI
Right putamen	34	0	−6	−4.41	161
Left putamen	−34	−2	−6	−4.52	171
Left precentral gyrus	−50	0	10	−5.18	242
Left middle cingulate gyrus	−2	−4	40	−4.91	385
Right middle frontal gyrus	42	8	54	−4.76	55

These clusters are referred to multiple comparisons correction using the FWE rate (a cluster-defining threshold of P=0.001 and a corrected cluster significance of P<0.05). AAL, automated anatomical labeling; MNI, Montreal Neurological Institute; HC, healthy control; MCI, mild cognitive impairment; aMCI, amnestic MCI; PD-MCI, Parkinson’s disease with MCI.