TABLE 1.
Molecular docking results between relevant proteins with berberine
| Protein type | Gene name | Affinity (Kcal/mol) |
|---|---|---|
| Immune‐related proteins | MAPK3 | −8.9 |
| MAPK8 | −8.6 | |
| TNF | −8.2 | |
| MAPK1 | −8.2 | |
| BAX | −8.1 | |
| NFκB1 | −7.3 | |
| CHUK | −7.3 | |
| IL6 | −6.9 | |
| NFκB1A | −6.4 | |
| CASP3 | −6.4 | |
| Host receptor | ACE2 | −9.8 |
| TMPRSS2 | −6.7 | |
| Viral proteins | 3CLpro | −6.7 |
| RdRp | −6.6 | |
| PLpro | −6.6 | |
| Spike | −6.5 |
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