Table 1. Mean value and ICC of PD-L1 scores using four assays.
| Assay | Immune cells | Tumor cells | ||
|---|---|---|---|---|
| PD-L1 score [%, mean (range*)] | Reader ICC (95% CI) | PD-L1 score [%, mean (range*)] | Reader ICC (95% CI) | |
| SP142 | 6.21 (0.1–27.7) | 0.602 (0.489–0.722) | 3.22 (0–47.0) | 0.684 (0.583–0.786) |
| SP263 | 11.43 (0.1–33.8) | 0.584 (0.464–0.710) | 9.07 (0–84.5) | 0.957 (0.937–0.974) |
| 22C3 | 12.90 (0.1–47.0) | 0.649 (0.530–0.764) | 8.20 (0–80.5) | 0.951 (0.927–0.970) |
| E1L3N | 10.65 (0.1–37.0) | 0.627 (0.511–0.744) | 7.17 (0–74.0) | 0.898 (0.853–0.936) |
PD-L1 = programmed death ligand 1; ICC = intraclass correlation coefficient; CI = confidence interval.
*Range of mean scores.