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. 2021 May 26;24(3):266–279. doi: 10.4048/jbc.2021.24.e29

Table 3. Pairwise comparison of programmed death ligand 1 scores of the four assays.

Pair of assays Immune cell score (%) Tumor cell score (%)
Mean difference* (SD) Mixed effects p-value Mean difference* (SD) Mixed effects p-value
SP142 and SP263 −5.21 (5.47) < 0.0001 −5.85 (13.73) < 0.0001
SP142 and 22C3 −6.69 (8.38) < 0.0001 −4.98 (11.70) < 0.0001
SP142 and E1L3N −5.18 (6.89) < 0.0001 −3.95 (10.24) < 0.0001
SP263 and 22C3 −1.47 (4.30) < 0.0001 0.87 (6.36) 0.1950
SP263 and ElL3N 0.03 (2.99) 0.9314 1.90 (4.96) < 0.0001
22C3 and E1L3N 1.50 (3.84) 0.0001 1.03 (3.24) < 0.0001

SD = standard deviation.

*Mean difference of 30 cases assessed by 10 pathologists; mixed-effects linear model (pathologists as random effects) after log-transformation.