TABLE 2.

Comparison of ovarian tissue cryopreservation and in vitro maturation results according to age groups (n = 133).

	1–5 years (n = 13)	6 years-menarche (n = 27)	Menarche-17 years (n = 35)	18–24 years (n = 33)	25–29 years (n = 14)	30–35 years (n = 11)	p-value
No. of ampules preserveda	8.2 ± 1.9b	10.4 ± 2.6c	12.9 ± 2.6	14.2 ± 3.0	14.0 ± 2.8	12.3 ± 3.4	<0.001
No. of oocytes retrieved per patient	9.0 ± 7.0	11.2 ± 6.2	11.4 ± 8.5	10.5 ± 7.4	9.9 ± 11.7	6.0 ± 6.4	0.073
No. of oocytes matured per patient	0.4 ± 0.7d,e	2.4 ± 2.4	3.4 ± 3.3	3.6 ± 3.3	2.1 ± 3.5	0.5 ± 0.9d	<0.001
No. of patients with matured oocytes	4 (30.8%)e	20 (74.1%)	30 (85.7%)	26 (78.8%)	7 (50.0%)	4 (33.3%)	<0.001
Maturation rate per patient (%)	4.6 ± 0.1d	23.8 ± 22.2	28.4 ± 21.5	38.3 ± 26.8	19.3 ± 19.3	8.9 ± 12.3d	<0.001
Overall maturation rate	5/117 (4.3%)f	65/302 (21.5%)	118/398 (29.7%)	118/348 (32.9%)	30/139 (21.6%)	6/66 (9.1%)g	<0.001

Data are given as mean ± SD, n (%) or n/N (%).

^aReflecting tissue volume. Each ampule contains 10 slivers of ovarian tissue for grafting.

^bTukey’s Studentized Range test showed a significant difference (p < 0.001) when compared to the menarche – 35 years age groups.

^cTukey’s Studentized Range test showed a significant difference (p < 0.001) when compared to the menarche – 29 years age groups.

^dTukey’s Studentized Range test showed a significant difference (p < 0.001) when compared to the 18–24 years group.

^eTukey’s Studentized Range test showed a significant difference (p < 0.001) when compared to the menarche-17 years group.

^fTukey’s Studentized Range test showed a significant difference (p < 0.001) when compared to the 6–29 years age groups.

^gTukey’s Studentized Range test showed a significant difference (p < 0.001) when compared to the menarche-17 and 18–24 years age groups.