Table 3.
Candidate drugs for COVID‐19 treatment and genes they interact with (http://ctdbase.org).
|
|
Genes connected with potential COVID‐19 treatment |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Drug |
ACE2 |
AGT |
CCL2 |
CCL3 |
CRP |
CSF3 |
IL1B |
IL2 |
IL2RA |
IL6 |
IL7 |
IL10 |
CXCL8 |
CXCL10 |
TNF |
|
Salvianolic acid B |
|
|
|
|
+ |
|
+ |
|
|
+ |
|
|
|
|
+ |
|
Atorvastatin |
+ |
+ |
+ |
|
+ |
|
+ |
|
+ |
+ |
|
|
+ |
+ |
+ |
|
Naringin |
|
+ |
+ |
+ |
|
|
+ |
+ |
|
+ |
|
+ |
+ |
|
+ |
|
Montelukast |
|
+ |
+ |
|
|
|
+ |
|
|
+ |
|
|
+ |
|
+ |
|
Dipyridamole |
|
|
+ |
|
|
|
+ |
+ |
|
+ |
|
|
|
|
+ |
|
Lopinavir |
|
|
+ |
+ |
|
|
+ |
|
|
+ |
|
|
|
|
+ |
|
Fulvestrant |
|
+ |
+ |
|
|
+ |
+ |
|
|
+ |
|
+ |
+ |
+ |
+ |
|
Ritonavir |
|
|
+ |
+ |
|
|
|
|
|
+ |
+ |
|
+ |
+ |
+ |
|
Telmisartan |
+ |
+ |
+ |
|
+ |
|
+ |
|
|
+ |
|
+ |
+ |
|
+ |
|
Bazedoxifene |
|
|
|
|
|
|
|
|
|
+ |
|
|
|
+ |
|
|
Bortezomib |
|
|
+ |
+ |
|
|
|
+ |
|
+ |
|
+ |
+ |
|
+ |
|
Atazanavir |
|
|
+ |
+ |
|
|
|
|
|
|
|
|
|
|
|
|
Ramipril |
|
+ |
+ |
||||||||||||
This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.