Table 3.
Evolution of graft function and CNI levels with time in patients with recovery vs. no recovery.
| Variable | Graft function recovered (n = 17) | Graft function not recovered (n = 25) | P value |
|---|---|---|---|
| Serum creatinine (mg/dl) | |||
| At baseline | 1.30 ± 0.38 | 1.72 ± 0.89 | 0.045 |
| Peak during COVID‐19 | 2.29 ± 1.23 | 3.97 ± 2.64 | 0.009 |
| At 3‐month follow‐up | 1.40 ± 0.36 | 3.63 ± 3.24 | 0.008 |
| At last follow‐up | 1.42 ± 0.54 | 3.73 ± 3.25 | 0.002 |
| Estimated GFR CKD‐EPI (ml/min/1.73 m2) | |||
| At baseline | 68.60 ± 21.17 | 54.70 ± 19.79 | 0.037 |
| At 3‐month follow‐up | 63.27 ± 19.7 | 33.67 ± 18.18 | <0.001 |
| At last follow‐up | 63.87 ± 19.90 | 35.42 ± 20.45 | <0.001 |
| Proteinuria(mg/day) | |||
| At baseline | 100 [65–216] | 400 [110–1200] | 0.015 |
| Peak during COVID‐19 | 120 [64–305] | 890 [135–2400] | 0.002 |
| At 3‐month follow‐up | 110 [65–330] | 960 [120–2250] | <0.001 |
| At last follow‐up | 100 [70–405] | 1100 [119.5–2400] | 0.001 |
| Tacrolimus trough concentration (ng/ml) | |||
| At baseline* | 5.06 ± 1.22 | 5.87 ± 1.95 | 0.178 |
| Peak during COVID‐19† | 7.41 ± 6.36 | 6.26 ± 3.56 | 0.516 |
| At 3‐month follow‐up‡ | 5.49 ± 1.82 | 5.18 ± 2.72 | 0.742 |
| At last follow‐up§ | 4.31 ± 2.04 | 5.06 ± 1.82 | 0.509 |
Missing data for * N = 8, † N = 10, ‡ n = 12, § n = 28.
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