Figure 1.

circHNRNPH1 Was Increased in the Postischemic Heart

(A) Validation of circHNRNPH1 by RNase R. (B) Schematic illustration of circHNRNPH1 formation. (C) Validation of the junction site of circHNRNPH1 by Sanger sequencing. (D and E) Cardiac circHNRNPH1 (D) and linear HNRNPH1 (E) expression assays in the rat ischemic heart at the 5th week after myocardial infarction (MI). Data are presented as the mean ± SD (n = 3 per group, ∗p < 0.05). (F) circHNRNPH1 expression in primary cardiomyocytes, cardiac fibroblasts, and vascular endothelial cells (VECs). Data are presented as the mean ± SD (n = 3 per group, ∗p < 0.05).