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. 2021 Jun 22;16(15):2288–2314. doi: 10.1002/cmdc.202100079

Figure 5.

Figure 5

Top panel discusses similarities between aspartate and cysteine proteases. Below, other compounds discussed and their possible functions. Note in camostat, the red moiety becomes bound to the target protease (see red mechanistic arrow), and this moiety is identical to that in nafamostat (above).