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. 2021 May 7;13(2):375–385. doi: 10.1111/jdi.13555

Table 3.

Adjusted association of lifestyle change with body weight change during the coronavirus disease 2019 pandemic

Regression coefficient for bodyweight change (as a continuous variable; linear regression model) Odds ratio for clinically important bodyweight change (cumulative link model)
Multivariate model 1
Leisure time physical activities −0.49 [−0.81 to −0.17] (P = 0.003) 0.68 [0.51 to 0.90] (P = 0.008)
Other physical activities 0.16 [−0.16 to 0.49] (P = 0.32) 1.14 [0.86 to 1.50] (P = 0.37)
Amount of meals 1.22 [0.76 to 1.68] (P < 0.001) 2.64 [1.85 to 3.77] (P < 0.001)
Amount of snacks 0.48 [0.14 to 0.82] (P = 0.007) 1.32 [0.97 to 1.80] (P = 0.074)
Multivariate model 2 (adjusted for patient attributes)
Leisure time physical activities −0.47 [−0.78 to −0.15] (P = 0.004) 0.70 [0.53 to 0.92] (P = 0.012)
Other physical activities 0.22 [−0.10 to 0.54] (P = 0.18) 1.18 [0.88 to 1.57] (P = 0.26)
Amount of meals 1.23 [0.78 to 1.69] (P < 0.001) 2.70 [1.89 to 3.85] (P < 0.001)
Amount of snacks 0.42 [0.09 to 0.74] (P = 0.013) 1.28 [0.94 to 1.73] (P = 0.12)
Multivariate model 3
Leisure time physical activities −0.47 [−0.79 to −0.16] (P = 0.004) 0.68 [0.51 to 0.91] (P = 0.010)
Other physical activities 0.14 [−0.19 to 0.47] (P = 0.41) 1.08 [0.81 to 1.44] (P = 0.59)
Amount of meals
With decline in eating out 1.64 [1.08 to 2.20] (P < 0.001) 3.70 [2.28 to 6.01] (P < 0.001)
Without decline in eating out 0.79 [0.16 to 1.43] (P = 0.016) 1.79 [1.07 to 2.98] (P = 0.026)
Amount of snacks 0.46 [0.12 to 0.79] (P = 0.009) 1.30 [0.96 to 1.77] (P = 0.092)
Multivariate model 4 (adjusted for patient attributes)
Leisure time physical activities −0.46 [−0.78 to −0.14] (P = 0.005) 0.70 [0.53 to 0.93] (P = 0.014)
Other physical activities 0.17 [−0.15 to 0.50] (P = 0.29) 1.11 [0.83 to 1.48] (P = 0.50)
Amount of meals
With decline in eating out 1.64 [1.09 to 2.19] (P < 0.001) 3.76 [2.30 to 6.16] (P < 0.001)
Without decline in eating out 0.81 [0.19 to 1.44] (P = 0.012) 1.83 [1.10 to 3.03] (P = 0.020)
Amount of snacks 0.39 [0.07 to 0.71] (P = 0.018) 1.25 [0.92 to 1.69] (P = 0.15)

Data are regression coefficients [95% confidence intervals] for the percentage change of bodyweight (%; as a continuous variable) and odds ratios [95% confidence intervals] for clinically important percentage change of bodyweight (i.e., by ≥3%). Each lifestyle change was coded as “decreased” (−1 point), “unchanged” (0 point) and “increased” (1 point). The explanatory variables entered in multivariate models 1 and 3 were lifestyle changes (see below) and medication changes, whereas multivariate models 2 and 4 were further adjusted for patient attributes (sex, age, type of diabetes, duration of diabetes, hypertension, dyslipidemia and medication use). Lifestyle changes entered in multivariate models 1 and 2 were the change of leisure time physical activities, other outside physical activities, the amount of meals and the amount of snacks, whereas in multivariate models 3 and 4, the amount of meals was stratified according to the decline in eating out.