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. 2021 Jul 1;58(1):111–120. doi: 10.1002/uog.23642

Table 6.

Adverse prenatal composite outcome (APCO)* and individual adverse perinatal outcomes in 106 pregnant women who were positive for SARS‐CoV‐2 infection, according to COVID‐19 symptoms

Outcome Asymptomatic (n = 57) Symptomatic (n = 49) P Mild symptoms (n = 30) Severe symptoms (n = 19)
APCO 10 (17.5) 9 (18.4) 1.0 3 6
Abnormal Doppler findings 5 (8.7) 3 (6.1) 0.72 1 2
SGA fetus with or without abnormal Doppler findings 7 (12.3) 5 (10.2) 0.8 2 3
Fetal death 2 (3.5) 0 0.5  0 0
Oligohydramnios 1 (1.8) 2 (4.1) 0.6 1 1
Abnormal BPP 2 (3.5) 2 (4.1) 1.0 1 1
Preterm delivery ≤ 35 weeks 9 (15.8) 13 (26.5) 0.23 9 4
Low birth weight (< 10th centile) 7 (12.3) 5 (10.2) 0.77 2 3
1‐min Apgar score ≤ 6 7 (12.3) 5 (10.2) 0.8 4 1
5‐min Apgar score ≤ 6 3 (5.3) 2 (4.1) 1.0 1 1

Data are given as n (%) or n.

*

APCO included any one or more of: small‐for‐gestational age (SGA), oligohydramnios (defined as amniotic fluid index < 5 and/or maximum vertical pocket < 2 cm), abnormal fetal biophysical profile (BPP), abnormal Doppler velocimetry and fetal death.