TABLE 2.
Multivariable logistic regression analysis of antibiotics use (n = 990).
| Characteristic | Odds ratio | p‐value | 95% confidence interval | |
|---|---|---|---|---|
| Lower bound | Upper bound | |||
| Sex | ||||
| Male | Ref. | |||
| Female | 1.50 | 0.040 | 1.02 | 2.21 |
| Age group | ||||
| 0 year | Ref. | |||
| 1–2 years | 0.63 | 0.118 | 0.35 | 1.13 |
| 3–5 years | 0.82 | 0.556 | 0.43 | 1.58 |
| 6–11 years | 1.13 | 0.670 | 0.65 | 1.98 |
| 12–17 years | 0.92 | 0.821 | 0.47 | 1.82 |
| Immunosuppressants, immunodeficiency or chemo | ||||
| No | Ref. | |||
| Yes | 1.65 | 0.451 | 0.45 | 6.05 |
| Hospitalization | ||||
| No | Ref. | |||
| Yes, without intensive care | 6.87 | <0.001 | 4.34 | 10.89 |
| Yes, with intensive care | 9.60 | <0.001 | 2.77 | 33.27 |
| Pyrexia (≥38.0/≥100.4°C/°F) | ||||
| No | Ref. | |||
| Yes | 1.84 | 0.011 | 1.15 | 2.96 |
| Upper respiratory tract infection | ||||
| No | Ref. | |||
| Yes | 1.08 | 0.730 | 0.71 | 1.65 |
| Diarrhea and/or vomiting | ||||
| No | Ref. | |||
| Yes | 1.05 | 0.822 | 0.67 | 1.64 |
| Lower respiratory tract infection | ||||
| No | Ref. | |||
| Yes | 0.34 | 0.007 | 0.16 | 0.74 |
| Headache | ||||
| No | Ref. | |||
| Yes | 0.88 | 0.746 | 0.42 | 1.87 |
| Chest X‐ray abnormalities | ||||
| No | Ref. | |||
| Yes | 4.40 | <0.001 | 1.99 | 9.71 |
| Oxygen support, mechanical ventilation and/or CPAP | ||||
| No | Ref. | |||
| Yes | 2.21 | 0.050 | 1.002 | 4.88 |
| Administration of systemic corticosteroids | ||||
| No | Ref. | |||
| Yes | 4.39 | <0.001 | 2.01 | 9.58 |
| MIS‐C diagnosis | ||||
| No | Ref. | |||
| Yes, w/o cardiac involvement | 10.35 | 0.050 | 1.005 | >100 |
| Yes, w/ cardiac involvement | 45.48 | 0.011 | 2.44 | >100 |
| Center | ||||
| Hospital San Bartolomé (PE) | Ref. | |||
| Hospital Nacional de Niños (CR) | 0.58 | 0.034 | 0.34 | 0.96 |
| Hospital Isidoro Iriarte (AR) | 0.25 | <0.001 | 0.14 | 0.46 |
| Hospital Edgardo Rebagliati Martins (PE) | 0.04 | 0.014 | 0.00 | 0.53 |
| Hospital Pablo Tobón Uribe (CO) | 0.05 | <0.001 | 0.01 | 0.25 |
| Clínica Jasmédica (PE) | 1.48 | 0.466 | 0.51 | 4.28 |
| Hospital General Regional 200 Tecámac (MX) | 12.24 | 0.045 | 1.06 | >100 |
This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.