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. 2021 Aug 6;73(9):1322–1331. doi: 10.1002/acr.24611

Table 4.

Reasons for medication change by type of change and physician approval*

Reason for medication change Stopped/delayed medication Changed medication dose
All

Not approved

by physician

Approved by

physician

P All

Not approved

by physician

Approved by

physician

P
Total 153 (100) 68 (44.4) 81 (52.9) 68 (100) 23 (33.8) 45 (66.2)
Did not work 13 (8.5) 1 (1.5) 12 (14.8) 0.004 3 (4.4) 1 (4.3) 2 (4.4) 0.985
Side effects 18 (11.8) 4 (5.9) 14 (17.3) 0.033 6 (8.8) 0 (0.0) 5 (11.1) 0.097
Cost 2 (1.3) 2 (2.9) 0 (0.0) 0.120 0 (0.0) 0 (0.0) 0 (0.0)
Canceled/postponed appointments 20 (13.1) 16 (23.5) 4 (4.9) 0.001 0 (0.0) 0 (0.0) 0 (0.0)
Not available 5 (3.3) 5 (7.4) 0 (0.0) 0.013 6 (8.8) 2 (8.7) 3 (6.7) 0.762
Worried about COVID‐19 60 (39.2) 37 (54.4) 20 (24.7) 0.000 12 (17.6) 6 (26.1) 6 (13.3) 0.192
Other illness/infection 24 (15.7) 9 (13.2) 15 (18.5) 0.382 2 (2.9) 0 (0.0) 2 (4.4) 0.305
Loss of insurance 3 (2.0) 3 (4.4) 0 (0.0) 0.056 1 (1.45) 0 (0.0) 1 (2.2) 0.471
Having a disease flare 4 (2.6) 0 (0.0) 4 (4.9) 0.063 28 (41.2) 9 (39.1) 19 (42.2) 0.806
Surgery/medical procedure 8 (5.2) 2 (2.9) 6 (7.4) 0.228 0 (0.0) 0 (0.0) 0 (0.0)
Doctor recommended, unspecified reason 3 (2.0) 0 (0.0) 3 (3.7) 0.109 2 (2.9) 0 (0.0) 2 (4.4) 0.305
No longer needed (e.g., disease flare over) 7 (4.6) 0 (0.0) 7 (8.6) 0.013 6 (8.8) 4 (17.4) 2 (4.4) 0.075
Other 14 (9.2) 4 (5.9) 9 (11.1) 0.260 9 (13.2) 2 (8.7) 7 (15.6) 0.430
*

Values are the number (%). Values reflect number of changes and not number of patients. Respondents could select more than one reason. Four patients did not indicate if their decision to stop medication was physician approved.