Table 2.
Predictors of being placed on mechanical ventilation and mortality among COVID‐19 positive patients according to anemia status
| Non‐anemic patients (n = 1770) | ||
|---|---|---|
| Variable | Mechanical ventilation HR adj a (95% CI) | Mortality HR adj a (95% CI) |
| RDW (%) >15 versus ≤15 | 1.66 (1.19–2.32) | 1.60 (1.18–2.15) |
| Female versus male | 0.65 (0.52–0.82) | 0.69 (0.55–0.85) |
| Non‐Hispanic white versus Hispanic and/or nonwhite | 0.73 (0.56–0.95) | 0.90 (0.71–1.14) |
| Age (years) | ||
| <52 | 1.0 (Ref) | 1.0 (Ref) |
| ≥52–63 | 1.91 (1.39–2.67) | 1.93 (1.25–2.98) |
| 64–75 | 2.46 (1.77–3.42) | 3.42 (2.29–5.13) |
| >75 | 1.81 (1.23–2.65) | 6.63 (4.41–9.96) |
| Charlson comorbidity index | 0.97 (0.91–1.04) | 1.03 (0.98–1.09) |
| Anemic patients (n = 792) | ||
| RDW (%) >15 versus ≤15 | 0.91 (0.66–1.25) | 0.96 (0.74–1.25) |
| Female versus male | 0.99 (0.72–1.36) | 0.76 (0.58–0.99) |
| Non‐Hispanic white versus Hispanic and/or nonwhite | 1.08 (0.76–1.54) | 1.23 (0.94–1.62) |
| Age (years) | ||
| <52 | 1.0 (Ref) | 1.0 (Ref) |
| ≥ 52–63 | 1.37 (0.76–2.46) | 4.94 (2.22–11.03) |
| 64–75 | 2.31 (1.37–3.91) | 6.88 (3.17–14.97) |
| >75 | 1.48 (0.86–2.57) | 10.10 (4.67–21.76) |
| Charlson comorbidity index | 1.02 (0.95–1.09) | 1.07 (1.01–1.12) |
Note: The High RDW*Anemia interaction term was statistically significant for both mechanical ventilation (p = .02) and mortality (p = .01).
Abbreviations: CI, confidence interval; COVID‐19, coronavirus disease 2019; HRadj, adjusted odds ratio; RDW, red cell distribution width; Ref, reference.
Adjusted for all variables listed.
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