TABLE 1.
Clinical characteristics of the study patients, stratified by the disease severity
| Characteristic | All COVID‐19 patients (N = 178) | Patients with severe disease (N = 73) | Patients with nonsevere disease (N = 105) |
|---|---|---|---|
| Age (years) | |||
| Median (interquartile ranges) | 57.5 (44.0–70.0) | 68.0 (59.0–77.0) | 49.0 (35.0–60.0) |
| Distribution no. (%) | |||
| 20–29 years | 17 (9.6) | 0 (0.0) | 17 (16.2) |
| 30–39 years | 18 (10.1) | 1 (1.4) | 17 (16.2) |
| 40–49 years | 30 (16.9) | 9 (12.3) | 21 (20.0) |
| 50–59 years | 30 (16.9) | 10 (13.7) | 20 (19.0) |
| 60–69 years | 33 (18.5) | 20 (27.4) | 13 (12.4) |
| 70–79 years | 32 (18.0) | 19 (26.0) | 13 (12.4) |
| 80–89 years | 15 (8.4) | 11 (15.1) | 4 (3.8) |
| 90–99 years | 3 (1.7) | 3 (4.1) | 0 (0.0) |
| Male sex no. (%) | 106 (59.6) | 47 (64.4) | 59 (56.2) |
| Severity no. (%) | |||
| Mild: Symptomatic without pneumonia | 30 (16.9) | ‐ | 30 (28.6) |
| Moderate: Symptomatic with pneumonia, no oxygen therapy | 75 (42.1) | ‐ | 75 (71.4) |
| Severe: Symptomatic with pneumonia, conventional oxygen therapy | 51 (28.7) | 51 (69.9) | ‐ |
| Critical: Admission to intensive care unit (ICU) or use of mechanical ventilation | 22 (12.4) | 22 (30.1) | ‐ |
| Pre‐existing medical conditions—no. (%) a | |||
| Hypertension | 48 (27.6) | 30 (42.9) | 18 (17.3) |
| Diabetes | 33 (19.0) | 24 (34.3) | 9 (8.7) |
| Cardio vascular diseases | 10 (5.7) | 9 (12.9) | 1 (1.0) |
| DRB1 genotype—no. (%) b | |||
| 09:01/09:01 | 5 (2.8) | 5 (6.8) | 0 (0.0) |
| 09:01/X | 41 (23.0) | 19 (26.0) | 22 (21.0) |
| X/X | 132 (74.2) | 49 (67.1) | 83 (79.0) |
a
Information on pre‐existing medical conditions was acquired from 174 patients (70 severe cases and 104 nonsevere cases) with COVID‐19.
b
X stands for any other DRB1 allele.