TABLE 1.
Baseline characteristics of 932 patients with coronavirus disease 2019 (COVID‐19)
| Total (N = 932) | Non‐severe disease (n = 880) | Severe disease (n = 52) | P value | |
|---|---|---|---|---|
| Age, y (median [IQR]) | 58 (48‐67) | 57 (48‐66) | 70 (62‐80) | <0.0001 |
| Distribution, n (%) | <0.0001 | |||
| 14‐49 | 250 (26.8) | 247 (28.1) | 3 (5.8) | |
| 50‐64 | 369 (39.6) | 356 (40.4) | 13 (25.0) | |
| ≥65 | 313 (33.6) | 277 (31.5) | 36 (69.2) | |
| Sex (n, %) | <0.0001 | |||
| Male | 375 (40.2) | 340 (38.6) | 35 (67.3) | |
| Female | 557 (59.8) | 540 (61.4) | 17 (32.7) | |
| Current smoker (n, %) | 124 (13.3) | 112 (12.7) | 12 (23.1) | 0.0327 |
| Current drinker (n, %) | 73 (7.8) | 65 (7.4) | 8 (15.4) | 0.0370 |
| Body mass index, kg/m2 (median [IQR]) | 23.4 (21.4‐25.4) | 23.4 (21.4‐25.4) | 24.0 (21.2‐25.7) | 0.6489 |
| Comorbidities (n, %) | ||||
| Any a | 489 (52.5) | 451 (51.3) | 38 (73.1) | 0.0022 |
| Hypertension | 287 (30.8) | 265 (30.1) | 22 (42.3) | 0.0642 |
| Diabetes | 134 (14.4) | 122 (13.9) | 12 (23.1) | 0.0658 |
| ASCVD | 78 (8.4) | 67 (7.6) | 11 (21.2) | 0.0006 |
| COPD | 29 (3.1) | 23 (2.6) | 6 (11.5) | 0.0003 |
| Asthma | 9 (1.0) | 7 (0.8) | 2 (3.8) | 0.0288 |
| Chronic renal disease | 11 (1.2) | 9 (1.0) | 2 (3.8) | 0.067 |
| Chronic liver disease | 39 (4.2) | 39 (4.4) | 0 (0) | 0.1209 |
| Cancer b | 29 (3.1) | 23 (2.6) | 6 (11.5) | 0.0003 |
| Tuberculosis | 17 (1.8) | 17 (1.9) | 0 (0) | 0.3118 |
| HBV infection c | 28 (3.0) | 28 (3.2) | 0 (0) | 0.1915 |
| Neuropsychiatric disorder | 19 (2.0) | 18 (2.05) | 1 (1.9) | 0.9516 |
Note: P values were calculated by the Mann‐Whitney U test, χ 2 test, or Fisherʼs exact test, when appropriate.
Abbreviations: ASCVD, arteriosclerotic cardiovascular disease; COPD, chronic obstructive pulmonary disease; HBV, hepatitis B virus; IQR, interquartile range.
a
Any type of comorbidity.
b
Any type of cancer.
c
The presence of HBV infection was defined as a positive result for hepatitis B surface antigen with or without elevated levels of alanine or aspartate aminotransferase.