TABLE 1.

Patients characteristic and adverse mucous‐cutaneous reactions in 6 patients after the first dose of Pfizer‐BioNTech vaccine

	Patient 1	Patient 2	Patient 3	Patient 4	Patient 5	Patient 6
Gender	Female	Female	Male	Female	Female	Female
Age	24	31	28	58	44	54
Personal atopy	Allergic rhinitis	Allergic rhinitis	Allergic rhinitis	Allergic rhinitis and asthma	Allergic rhinitis	Allergic rhinitis, atopic dermatitis
Allergy history	–	–	–	–	–	Contact allergy (nichel sulphate, fragrances)
Type of reaction	Generalized acute urticaria	Angioedema (tongue, gums)	Generalized acute urticaria	Flushing of the face	Flushing of the face	Angioedema (tongue, lips)
Time of onset	5 min	24 h	5 min	30 min	20 min	10 min
Treatment	Betametasone sodium phosphate (IV)	–	–	–	–	–