Table 2.
Comparison of HLA‐A genotype frequencies in mild, ICU, and fatal groups
|
Mild N = 128 F (%) |
ICU N = 62 F (%) |
Fatal N = 40 F (%) |
Mild versus ICU p‐value |
Mild versus fatal p‐value |
ICU versus fatal p‐value |
|
|---|---|---|---|---|---|---|
| A*01 | 14 (10.9) | 10 (16.1) | 5 (12.5) | 0.313a | 0.785a | 0.613a |
| A*02 | 24 (18.8) | 10 (16.1) | 8 (20.0) | 0.659a | 0.861a | 0.617a |
| A*03 | 8 (6.3) | 4 (6.5) | 3 (7.5) | 0.957b | 0.780 | 0.838b |
| A*11 | 18 (14.1) | 13 (21.0) | 9 (22.5) | 0.227a | 0.205a | 0.854a |
| A*23 | 1 (0.8) | 1 (1.6) | 1 (2.5) | 0.598b | 0.382b | 0.752b |
| A*24 | 21 (16.4) | 4 (6.5) | 3 (7.5) | 0.057b | 0.160b | 0.838b |
| A*26 | 6 (4.7) | 6 (13.6) | 3 (7.5) | 0.185a | 0.490b | 0.705b |
| A*29 | 3 (2.3) | 0 (0.0) | 0 (0.0) | NA | NA | NA |
| A*30 | 0 (0.0) | 1 (1.6) | 1 (2.5) | NA | NA | 0.752 |
| A*31 | 5 (3.9) | 1 (1.6) | 1 (2.5) | 0.397b | 0.676b | 0.752b |
| A*32 | 6 (4.7) | 1 (1.6) | 1 (2.5) | 0.291b | 0.546b | 0.752b |
| A*33 | 15 (11.7) | 5 (8.1) | 2 (5.0) | 0.462a | 0.219b | 0.536b |
| A*68 | 7 (5.5) | 3 (4.8) | 3 (7.0) | 0.855b | 0.636b | 0.577b |
Note: The comparison between the two groups was performed with Fisher's exact test or the Χ 2 test, as appropriate, at p = 0.05; N, number of alleles; NA, not applicable; F(%), allele frequency.
a
Χ 2 test.
b
Fisher's exact test.
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