Table 4.
Comparison of HLA‐C genotype frequencies in mild, ICU, and fatal subjects
|
Mild N = 128 F (%) |
ICU N = 62 F (%) |
Fatal N = 40 F (%) |
Mild versus ICU p‐value |
Mild versus fatal p‐value |
ICU versus fatal p‐value |
|
|---|---|---|---|---|---|---|
| C*01 | 5 (3.9) | 5 (8.1) | 3 (7.5) | 0.229a | 0.352b | 0.276b |
| C*02 | 1 (0.8) | 1 (1.6) | 1 (2.5) | 0.598b | 0.382b | 0.752b |
| C*03 | 11 (8.6) | 3 (4.8) | 2 (5.0) | 0.353b | 0.458b | 0.971b |
| C*04 | 26 (20.3) | 7 (11.3) | 3 (7.5) | 0.124a | 0.061b | 0.530b |
| C*06 | 12 (9.4) | 11 (17.7) | 7 (17.5) | 0.097a | 0.157a | 0.975a |
| C*07 | 30 (23.4) | 15 (24.2) | 9 (22.5) | 0.909a | 0.902a | 0.844a |
| C*08 | 11 (8.6) | 4 (6.5) | 2 (5.0) | 0.608b | 0.458b | 0.761b |
| C*12 | 15 (11.7) | 4 (6.5) | 3 (7.5) | 0.257b | 0.451b | 0.838b |
| C*14 | 3 (2.3) | 3 (4.8) | 3 (7.5) | 0.357a | 0.125b | 0.577b |
| C*15 | 13 (10.2) | 6 (9.7) | 5 (12.5) | 0.918a | 0.676a | 0.654a |
| C*16 | 1 (0.8) | 3 (4.8) | 2 (5.0) | 0.068b | 0.786b | 0.971b |
Note: The comparison between the two groups was performed with Fisher's exact test or the Χ 2 test, as appropriate, at p = 0.05. N, number of alleles; NA, not applicable;
F%, allele frequency.
a
Χ 2 test.
b
Fisher's exact test.
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