Table 5.
Comparison of HLA‐DRB1 genotype frequencies in mild, ICU, and fatal subjects
|
Mild N = 128 F (%) |
ICU N = 62 F (%) |
Fatal N = 40 F (%) |
Mild versus ICU p‐value |
Mild versus fatal p‐value |
ICU versus fatal p‐value |
|
|---|---|---|---|---|---|---|
| DRB1*01 | 9 (7.0) | 4 (6.5) | 3 (7.5) | 0.882a | 0.927a | 0.838a |
| DRB1*03 | 15 (11.7) | 6 (13.6) | 4 (10.0) | 0.674b | 0.764a | 0.957a |
| DRB1*04 | 7 (5.5) | 5 (8.1) | 2 (5.0) | 0.490b | 0.909a | 0.550a |
| DRB1*07 | 20 (15.6) | 11 (17.7) | 6 (15.0) | 0.711b | 0.924b | 0.717b |
| DRB1*08 | 3 (2.3) | 0 (0.0) | 0 (0.0) | NA | NA | NA |
| DRB1*10 | 11 (8.6) | 6 (13.6) | 4 (10.0) | 0.806b | 0.785a | 0.957a |
| DRB1*11 | 9 (7.0) | 1 (1.6) | 1 (2.5) | 0.117a | 0.290a | 0.752a |
| DRB1*12 | 9 (7.0) | 2 (3.2) | 1 (2.5) | 0.292a | 0.290a | 0.832a |
| DRB1*13 | 9 (7.0) | 7 (11.3) | 7 (17.5) | 0.322b | 0.049a | 0.374b |
| DRB1*14 | 9 (7.0) | 4 (6.5) | 4 (10.0) | 0.882a | 0.540a | 0.515a |
| DRB1*15 | 27 (21.1) | 15 (24.2) | 7 (17.5) | 0.629b | 0.621b | 0.422b |
| DRB1*16 | 0 (0.0) | 1 (1.6) | 1 (2.5) | NA | NA | NA |
Note: The comparison between the two groups was performed with Fisher's exact test or the Χ 2 test, as appropriate, at p = 0.05; N, number of alleles; NA, not applicable; F%, allele frequency.
a
Χ 2 test.
b
Fisher's exact test.
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