FIGURE 4.

Annualized retinal layer thinning predicts DMT failure. Probability of DMT failure regarding disability worsening (a), relapse (b), and clinical disease activity (c) as predicted by annualized loss of GCIPL and pRNFL measured 12 and 24 months after DMT initiation. aLGCIPL, annualized loss of macular ganglion cell and inner plexiform layer; aLpRNFL, annualized loss of peripapillary retinal nerve fiber layer; CI, confidence interval; DMT, disease‐modifying treatment; HR, hazard ratio; M12, measured between baseline and 12 months after DMT initiation; M24, measured between baseline and 24 months after DMT initiation; ns, not significant.