Scheme 2.
Reaction conditions: 2 a–x (0.236 mmol), PdCl2 (10 mol %), L24 (40 mol %), 1 a,b (0.826 mmol), LiCl (0.283 mmol), H2O (26 μL), KOtBu (0.472 mmol, 1.0 m in THF), solvent (1.18 mL), room temperature, overnight.
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