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. 2021 Jul 2;26(2):1053–1076. doi: 10.1007/s11030-021-10230-6

Table 4.

The PASS prediction results of the biological activities of the coumarin phytochemicals series

No Biological activities Glycycoumarin Inophyllum P Mesuol Oxypeucedanin hydrate
Pa Pi Pa Pi Pa Pi Pa Pi
1 Membrane integrity agonist 0.937 0.002 0.683 0.058 0.720 0.051
2 HMOX1 expression enhancer 0.635 0.015 0.265 0.115 0.355 0.072
3 Chlordeconereductase inhibitor 0.803 0.02 0.243 0.193 0.344 0.132
4 HIF1A expression inhibitor 0.936 0.004 0.867 0.008 0.348 0.135 0.512 0.053
5 Histidine kinase inhibitor 0.709 0.008 0.765 0.005 0.467 0.035 0.498 0.029
6 Aldehyde oxidase inhibitor 0.807 0.009 0.654 0.023
7 Antimutagenic 0.877 0.003 0.735 0.005
8 Mucomembranous protector 0.648 0.081 0.307 0.234
9 TP53 expression enhancer 0.901 0.005 0.484 0.098 0.616 0.045 0.580 0.056
10 Chemopreventive 0.807 0.004 0.665 0.008 0.615 0.009 0.596 0.010

Pa: prediction of activity spectra for substances; Pi: probable inactivity