TABLE 2.
Levels of Aβ40 and Aβ42 for each administration
| Aβ40 | Aβ42 | |||||
|---|---|---|---|---|---|---|
| Mean ± SD; median (range) | P value vs previous administration | P value vs T0 | Mean ± SD; median (range) | P value vs previous administration | P value vs T0 | |
| T0 | 6437.5 ± 3201; 6000 (3100‐12 300), n = 8 | 577.3 ± 228; 631.5 (278‐915), n = 8 | ||||
| T1 | 5825 ± 1921.9 (3400‐8400), n = 8 | .528 | .528 | 604 ± 253.1; 609 (282‐952), n = 8 | .483 | .483 |
| T2 | 6260.4 ± 2277.9 (5130.5‐9718), n = 8 | .116 | .833 | 634.6 ± 266; 638 (303‐970), n = 8 | .012 a | .068 |
| T3 | 6522.5 ± 2394.1 (5855‐10 500), n = 8 | .401 | .944 | 627.6 ± 50.9 (277‐952; 660), n = 8 | .528 | .263 |
| T4 | 6842.9 ± 1391.5 (7100‐8600), n = 7 | .499 | .498 | 891 ± 462.2; 787 (295‐676), n = 7 | .018 a | .018 a |
a
Statistically significant (P ≤ .05).
Abbrevations: Aβ40, amyloid‐β40 peptide; Aβ42, amyloid‐β42 peptide; SD, standard deviation.