Table 2.
The relative level of histo-blood group carbohydrates expressed in tissues and exocrine secretions according to the combination of histo-blood group glycosyltransferases. Modified from Perry et al., 2007.
| Systems | Glycosyltransferases | OP type 1 | H | Lea | Leb | A type 1 | B type 1 | ALeb | BLeb | RBC phenotypes |
|---|---|---|---|---|---|---|---|---|---|---|
| ABO, Lewis, Secretor | FUTII + FUTIII + GTA | (+) | (+) | + | +++ | +++ | 0 | ++++ | 0 | A Le(a-b+) |
| ABO, Lewis, Secretor | FUTII + FUTIII + GTB | (+) | (+) | + | +++ | +++ | ++ | 0 | ++++ | B Le(a-b+) |
| ABO, Lewis, Secretor | FUTII + FUTIII + GTA + GTB | (+) | (+) | + | +++ | +++ | ++ | ++++ | ++++ | AB Le(a-b+) |
| ABO, Lewis, Secretor | FUTII + FUTIII | (+) | (+) | + | +++++ | O Le(a-b+) | ||||
| ABO, Lewis, Secretor | FUTII + GTA | + | ++ | +++++ | A Le(a-b-) | |||||
| ABO, Lewis, Secretor | FUTII + GTB | + | ++ | +++++ | B Le(a-b-) | |||||
| ABO, Lewis, Secretor | FUTII + GTA + GTB | + | ++ | +++++ | +++++ | AB Le(a-b-) | ||||
| ABO, Lewis, Secretor | FUTII | + | +++++ | O Le(a-b-) | ||||||
| ABO, Lewis, Non-Secretor | FUTIII + GTA | + | +++++ | A Le(a+b-) | ||||||
| ABO, Lewis, Non-Secretor | FUTIII + GTB | + | +++++ | B Le(a+b-) | ||||||
| ABO, Lewis, Non-Secretor | FUTIII + GTA + GTB | + | +++++ | AB Le(a+b-) | ||||||
| ABO, Lewis, Non-Secretor | FUTIII | + | +++++ | O Le(a+b-) |
OP, Oligosaccharide precursor; RBC, Red blood cell; (+): Very low expression; +, ++: Low expression; +++, ++++ Moderate expression; +++++: High expression.