TABLE 3.
Feasibility of the primary echocardiographic measurements of cardiac function and strain measurements
| Measure | Feasibility in CCS | Feasibility in siblings | p‐value |
|---|---|---|---|
| Biplane LV ejection fraction | 91% (1276/1402) | 96% (276/277) | 0.006 |
| Global longitudinal strain | 80% (1126/1402) | 91% (253/277) | <0.001 |
| Global circumferential strain | 86% (1212/1402) | 89% (247/273) | 0.21 |
| Diastolic function a | 99% (1384/1402) | 100% (277/277) | 0.10 |
| TAPSE | 98% (1380/1402) | 100% (277/277) | 0.02 |
| RV free wall strain | 57% (805/1402) | 65% (180/277) | 0.02 |
| LA reservoir strain | 72% (1013/1402) | 79% (218/277) | 0.03 |
Feasibility is shown as the % and n measurements possible out of all currently analyzed examinations: %, n/total.
Abbreviations: CCS, childhood cancer survivors; LA, left atrium; LV, left ventricle; RV, right ventricle; TAPSE, tricuspid annular plane systolic excursion.
a
At least 2 parameters available out of: LA volume, tricuspid regurgitation jet, e’ or E/e’. 29