TABLE 4.
Inter‐observer variability for the echocardiographic measurements in 30 patients
| Measure | Mean | Range | Absolute | Relative (%) a | ICC | ||||
|---|---|---|---|---|---|---|---|---|---|
| Difference ±SD | 95% LOA | p | Difference ±SD | 95% LOA | p | ||||
| LVEDD (mm) | 47.3 | 35 ‐ 62 | ‐0.2 ± 3.6 | ‐7.2 / 6.7 | 0.71 | 0 ± 9 | ‐17 / 16 | 0.84 | 0.82 |
| LVESD (mm) | 31.9 | 23 ‐ 52 | ‐1.9 ± 2.7 | ‐7.4 / 3.5 | 0.001 | ‐6 ± 9 | ‐25 / 12 | 0.002 | 0.87 |
| Septal thickness (mm) | 7.4 | 4 ‐ 11 | ‐0.7 ± 1.6 | ‐4.0 / 2.4 | 0.02 | ‐9 ± 22 | ‐52 / 35 | 0.047 | 0.51 |
| Posterior wall thickness (mm) | 8.8 | 6 ‐ 15 | ‐0.4 ± 1.8 | ‐4.0 / 3.0 | 0.20 | ‐6 ± 21 | ‐47 / 36 | 0.18 | 0.61 |
| Left atrial volume (ml) | 39.4 | 21 ‐ 84 | ‐2.8 ± 8.1 | ‐18.6 / 13.0 | 0.09 | ‐6 ± 21 | ‐47 / 34 | 0.15 | 0.83 |
| E wave (cm/s) | 81.1 | 46 ‐ 152 | 0.9 ± 4.7 | ‐8.3 / 10.0 | 0.33 | 1 ± 7 | ‐12 / 14 | 0.60 | 0.98 |
| A wave (cm/s) | 55.7 | 38 ‐ 148 | 0.2 ± 6.8 | ‐13.2 / 13.6 | 0.12 | 3 ± 12 | ‐20 / 26 | 0.15 | 0.94 |
| TDI LV e’ lateral (cm/s) | 14.6 | 6 ‐ 25 | 0.4 ± 0.8 | ‐1.2 / 1.9 | 0.01 | 3 ± 6 | ‐8 / 13 | 0.015 | 0.98 |
| TAPSE (mm) | 21.8 | 17 ‐ 33 | ‐2.0 ± 3.1 | ‐8.1 / 4.1 | 0.74 | ‐2 ± 13 | ‐28 / 24 | 0.35 | 0.72 |
| Fractional shortening (%) | 33.0 | 16 ‐ 45 | 3.7 ± 6.0 | ‐8.1 / 15.5 | 0.004 | 10 ± 20 | ‐29 / 49 | 0.02 | 0.63 |
| LV ejection fraction (%) b | 54.9 | 41 ‐ 66 | 1.8 ± 3.2 | ‐4.6 / 8.1 | 0.008 | 3 ± 6 | ‐9 / 16 | 0.02 | 0.85 |
| Global longitudinal strain (%) | ‐19.6 | ‐15 ‐ −27 | ‐0.2 ± 1.7 | ‐3.6 / 3.1 | 0.45 | 1 ± 8 | ‐16 / 18 | 0.52 | 0.76 |
| LV mechanical dispersion (msec) | 40.0 | 27 ‐ 58 | ‐1.5 ± 8.9 | ‐18.9 / 15.9 | 0.39 | 5 ± 24 | ‐53 / 43 | 0.30 | 0.66 |
| Global circumferential strain (%) | ‐20.9 | ‐17 ‐ −27 | ‐1.0 ± 1.7 | ‐4.1 / 2.0 | 0.000 | 5 ± 8 | ‐11 / 20 | 0.000 | 0.70 |
| RV free wall strain (%) | ‐32.1 | ‐27 ‐ −41 | ‐0.1 ± 1.7 | ‐3.4 / 3.2 | 0.72 | 0 ± 5 | ‐10 / 11 | 0.73 | 0.89 |
| LA reservoir strain (%) | 44.9 | 21 ‐ 64 | ‐0.8 ± 4.9 | ‐10.5 / 8.9 | 0.38 | ‐2 ± 11 | ‐24 / 19 | 0.25 | 0.89 |
Abbreviations: ICC, intra‐class correlation coefficient; LA, left atrium; LOA, limits of agreement; LV, left ventricle; LVEDD, LV end‐diastolic diameter; LVESD, LV end‐systolic diameter; RV, right ventricle; TAPSE, tricuspid annular plane excursion; TDI, Tissue Doppler Imaging.
a
As a percentage of the mean measurement of the two observers
b
autoEF n = 24; manual EF n = 4