Figure 2.
SMO may be regulated by BET inhibitor. Available CNV data for the SMO gene in prostate cancer from the datasets of (A) Robinson et al. 32 , (B) Beltran et al. 30 , and (C) Abida et al., 34 (D) LNCaP and C4‐2B cells were treated with JQ1 for 48 h, and the expression of SMO was assessed by real‐time PCR and western blot. *p < .05, versus the control group. AdPC, prostate adenocarcinoma; BET, bromodomain and extraterminal; CNV, copy number variation; NEPC, neuroendocrine prostate cancer; PCR, polymerase chain reaction; SMO, smoothened