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SMO expression is linked to the activation of AR signaling. GSEA (hallmark pathways) comparing “SMO‐lo” versus “SMO‐hi” prostate cancer transcriptomic samples revealed the most negatively enriched gene set, “ANDROGEN_RESPONSE.” AR, androgen receptor; FDR, false discovery rate; GSEA, gene set enrichment analysis; NES, normalized enrichment score [Color figure can be viewed at wileyonlinelibrary.com]
