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. 2021 May 14;27(34):8832–8845. doi: 10.1002/chem.202101229

Figure 7.

Figure 7

Binding mode of (R,R)‐trans‐δ‐viniferin and (S,S)‐trans‐δ‐viniferin when docked into ds10 duplex. The four panels represent the four possible 1 : 2 DNA/ligand complexes which can be formed between ds10 duplex and the two enantiomers targeting the minor and/or major grooves as follows: A) minor groove: (R,R)‐trans‐δ‐viniferin, major groove: (R,R)‐trans‐δ‐viniferin, B) minor groove: (S,S)‐trans‐δ‐viniferin, major groove: (S,S)‐trans‐δ‐viniferin, C) minor groove: (R,R)‐trans‐δ‐viniferin, major groove: (S,S)‐trans‐δ‐viniferin and D) minor groove: (S,S)‐trans‐δ‐viniferin, major groove: (R,R)‐trans‐δ‐viniferin. (R,R)‐trans‐δ‐viniferin and (S,S)‐trans‐δ‐viniferin are represented as cyan and green sticks, respectively.