Table 1.

Effect of test complexes (1 and 2) on cell growth after 72 h of incubation. Stock solutions of 1 and 2 were made in DMSO and the amount of added solvent was always lower than 0.5 %. Cisplatin, dissolved in 0.9 % NaCl, was used as reference.

Complex		IC50 [μm][a]				RF[b]
	A2780	A2780cis	HeLa	HT29	A549
1	2.19±0.06	2.15±0.19	7.93±0.71	4.85±0.99	6.60±1.90	1.0
2	2.99±0.19	3.45±0.34	7.05±0.72	4.40±1.10	7.80±1.90	1.1
cisplatin[c]	0.91±0.13	6.61±0.61	1.51±0.09	2.57±0.67	2.10±0.25	7.3

[a] IC₅₀ values are the mean±SD of at least three independent experiments in duplicate. [b] IC₅₀(A2780cis)/IC₅₀(A2780); [c] Ref. [22].