Table I.

Application of the low‐molecular‐weight heparin (LMWH)‐calibrated, universal assay.

Measure	Result
DOAC cut‐off value 30 µg/l	0·35 U/ml
DOAC cut‐off value 50 µg/l	0·58 U/ml
DOAC cut‐off value 100 µg/l	1·14 U/ml
Regression equation rivaroxaban	120 × [U/ml]−19
Regression equation apixaban	115 × [U/ml]−22
Regression equation edoxaban	164 × [U/ml]−24

Two options appear. First, cut‐off values for the clinical thresholds can be given. The corresponding categorial result is the most crucial information, which can prompt clinical decision making. Second, the regression equations can be used to calculate plasma concentrations of the individual drugs.