Table 1.
Demographic and clinical characteristics of study participants: results are expressed as percentages for categorical variables and mean ± SD or median [IQR] for continuous variables
| Variables | Frail (28) |
Non-frail (48) |
P-value |
|---|---|---|---|
| Gender, female, n (%) | 11 (39.3) | 24 (50) | 0.366 |
| Age (years) | 66.5 ± 10.5 | 57.9 ± 14.9 | 0.009 |
| BMI (kg * m−2) | 28.6 ± 6.3 | 29.2 ± 6.4 | 0.672 |
| Dialysis vintage (days) | 449 [881] | 497 [891] | 0.690 |
| CCI (score) | 6 ± 2.1 | 4.8 ± 2.3 | 0.032 |
| Diabetes mellitus, n (%) | 9 (32.1) | 11 (22.9) | 0.378 |
| Vascular access type, n (%) | |||
| Arteriovenous fistula | 15 (53.6) | 35 (74.5) | 0.063 |
| Central-venous | 13 (46.4) | 12 (25.5) | 0.063 |
| Medications (n°) | 13.3 ± 4.5 | 10.9 ± 2.9 | 0.015 |
| History of falls, n (%) | 16 (59.3) | 17 (35.4) | 0.046 |
| Laboratory values | |||
| Hb (g/dL) | 11.2 ± 1.1 | 11.2 ± 1.2 | 0.924 |
| CRP (mg/L) | 8 [24] | 6 [8] | 0.075 |
| Phosphate (mmol/L) | 1.3 ± 0.5 | 1.5 ± 0.6 | 0.084 |
| PTH (ρmol/L) | 24 [19.4] | 19.1 [16.8] | 0.177 |
| Albumin (g/L) | 36.5 [5.8] | 38 [4] | 0.015 |
| Adjusted calcium (mmol/L) | 2.4 ± 0.1 | 2.3 ± 0.1 | 0.475 |
| URR (%) | 70.8 ± 7 | 71.5 ± 5.4 | 0.635 |
| Creatinine (μmol/L) | 555 ± 147 | 680 ± 150 | 0.001 |
Abbreviations: SD Standard deviation, IQR Interquartile range, BMI Body mass index, CCI Charlson comorbidity index, HD Haemodialysis, Hb Hemoglobin, CRP C-reactive protein, PTH Parathyroid hormone, URR Urea reduction ratio