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. 2021 Apr 5;40(5):1419–1430. doi: 10.1002/etc.4994

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© 2021 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Dose–response curves for the acute toxicity experiments. Dose–response relationship for juvenile rainbow trout (Oncorhynchus mykiss) exposed to lampricides alone and in combination. (A) Dose response for 3‐trifluoromethyl‐4‐nitrophenol (TFM), either alone (orange) or in the presence of 1% niclosamide (Nic; red). (B) Dose response for Nic, either alone (blue) or in the presence of 100% TFM (red). n = 6 fish/tank, in triplicate, for each exposure concentration. Concentrations of TFM and Nic are plotted against percentage of survival. Insets denote the lethal concentration values calculated for each condition, along with the slopes of the dose–response curves.