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. 2021 Mar 10;14(8):1781–1804. doi: 10.1002/cssc.202100159

Scheme 12.

Scheme 12

One‐pot enzymatic cascade for the conversion of aldehyde into amino acid involving CO2‐fixation step catalyzed by TPP‐dependent decarboxylase (KdCA) and a reductive amination step catalyzed either by a transaminase (YbdL) or an amine dehydrogenase (LeuDH). [34] TPP=thiamine pyrophosphate, LeuDH=leucine dehydrogenase.