Scheme 12.

One‐pot enzymatic cascade for the conversion of aldehyde into amino acid involving CO2‐fixation step catalyzed by TPP‐dependent decarboxylase (KdCA) and a reductive amination step catalyzed either by a transaminase (YbdL) or an amine dehydrogenase (LeuDH). [34] TPP=thiamine pyrophosphate, LeuDH=leucine dehydrogenase.